Synthesis, mechanism and kinetic investigations of mono-2,6-dimethylphenyl phosphate in acid medium

摘要

Investigations of the kinetic study of the hydrolysis of mono-2,6-dimethylphenyl phosphate have been carried out in 0.1-6.0 mol dm~(-3) HCl and in buffers from 1.24 to 7.46 pH at 97 +- 0.5 deg C in water. The monoester has been found to be hydrolysed by conjugate acid, mononegative, neutral and dinegative supported by Arrhenius parameters, Zucker-Hammett hypothesis, concentration, solvent effect etc. A study of the reaction in dioxanewater mixture suggested the nature of transition state in which charges are developed due to the bimolecular attack of water molecule. Comparative isokinetic rate data of similarly substituted other phosphate monoesters, whose mechanism is known, supported P-O bond fission.