Synthesis, Structure and Biological Activities of 2,2-Dichloro-1-(4-ethoxyphenyl)-cyclopropanyl Substituted Piperidin-1-yl Ketone

摘要

Ten new amide-type compounds, which are pyrethroids containing piperidine, are synthesized from 1-(4-ethyoxyphenyl)-2,2-dichlorocyclopropane-1-carboxylic acid and substituted piperidine. Their structures were confirmed by ~1H NMR, MS and elemental analysis. The crystal structure of 4a and 4h were determined by X-ray diffraction analysis. The bioassay results indicated that they showed moderate activity.