2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: initiation and safety monitoring of therapeutic agents for the treatment of arthritis and systemic features.

摘要

Juvenile idiopathic arthritis (JIA) is defined by the International League of Associations for Rheumatology (ILAR) as arthritis of unknown etiology that begins before the sixteenth birthday and persists for at least 6 weeks with other known conditions excluded (1). JIA is one of the more common chronic diseases of childhood, with a prevalence of approximately 1 per 1,000 (2,3). JIA often persists into adulthood and can result in significant long-term morbidity, including physical disability (4-9).