Repetitive transcranial magnetic stimulation induced seizures in an adolescent patient with major depression: A case report

摘要

We report the following TMS-related seizure. The subject was a 16-year-old woman with Major Depressive Disorder according to DMS-IV-TR [1] as verified by using the Structured Clinical Interview for DSM Disorders (SCID I) [2], who was hospitalized because of recurrent depression. Her main clinical symptoms were depressive mood, anhedonia, suicidal ideation, insomnia, somatization and anxiety. She had been treated with different antidepressant drugs and atypical antipsychotics without clear-cut treatment response.Before rTMS treatment was started, the patient underwent a thorough physical examination. Both electrocardiogram (EKG) and cerebral magnetic resonance imaging scan (MRI) were normal. Routine laboratory test results (blood Cell count, liver function, urinalysis, renal function, electrolytes and thyroids function and drug abuse screen) were in the normal range.