N-Acetyl-L-cysteine enhances ex-vivo amplification of deciduous teeth dental pulp stem cells

摘要

Objective: Obtaining high number of stem cells is of interest for cell based therapies. N-Acetyl-L-cysteine (NAC) acts as a source of sulfhydryl groups and an anti-oxidative agent. The aim of this study was to test different NAC concentration on proliferation and differentiation of deciduous teeth dental pulp stem cells (DTSCs) in vitro as well as to define the possible underlining mechanism of its effect.