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Repeat testing of critical laboratory test results.

机译:重复测试关键实验室测试结果。

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摘要

Recent literature has explored the value of repeat testing of alert or critical laboratory test results, as illustrated in the article by Toll et al. Using a large data set for selected tests, that article makes the point that repeat testing is rarely of value. All too often, laboratories retest results that are considered "critical" because of a purely emotional desire to avoid misleading a clinician into taking an action on that result, even though there is no scientific basis for retesting. The basic problem with such studies is an intrinsic bias in only retesting critical values to detect false-positive (a error) results. Because none of the noncritical specimens were retested to detect false-negative results, the beta error is not evaluated. In other words, perhaps the patient really had a critical test result, but it was falsely noncritical.
机译:如Toll等人在文章中所阐明的,最近的文献探索了重复测试警报或关键实验室测试结果的价值。该文章将大量数据用于选定的测试,这表明重复测试几乎没有价值。实验室常常会重新测试被认为是“关键”结果,因为纯粹出于情感上的愿望,以避免误导临床医生对该结果采取措施,即使没有重新测试的科学依据。此类研究的基本问题是仅重新测试关键值以检测假阳性(错误)结果的固有偏差。由于没有对所有非关键样本进行重新测试以检测假阴性结果,因此不会评估beta误差。换句话说,也许患者确实有一个严格的检查结果,但是那是错误的非严格的。

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