NAD+ and mtRNA sensing drive human kidney diseases

Itoh Hiroshi; Yoshino Jun

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NAD+ and mtRNA sensing drive human kidney diseases

机译：NAD+ 和 mtRNA 传感驱动人类肾脏疾病

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Defective nicotinamide adenine dinucleotide (NAD+) metabolism is involved in various diseases. A study in Nature Metabolism identifies the cytosolic mitochondrial-RNA sensing system as a mediator that links NAD+ deficiency to kidney disease in humans and mice.

机译：有缺陷的烟酰胺腺嘌呤二核苷酸(NAD +)代谢参与了各种疾病。研究自然界中新陈代谢标识胞质线粒体转录rna传感系统中介将NAD +不足与肾脏疾病在人类和老鼠。

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来源
《Nature Metabolism》 |2023年第3期|357-359|共3页
作者
Itoh Hiroshi; Yoshino Jun;
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Keio University School of Medicine;

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正文语种英语
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1. NAD + and mtRNA sensing drive human kidney diseases [J] . Itoh Hiroshi, Yoshino Jun Nature Metabolism . 2023,第3期

机译：NAD + and mtRNA sensing drive human kidney diseases
2. Modeling human disease: a mouse model of acute kidney injury to chronic kidney disease progression after cardiac arrest [J] . Terker Andrew Scott, de Caestecker Mark Kidney international. . 2020,第1期

机译：Modeling human disease: a mouse model of acute kidney injury to chronic kidney disease progression after cardiac arrest
3. Genomic approaches to the burden of kidney disease in Sub-Saharan Africa: the Human Heredity and Health in Africa (H3Africa) Kidney Disease Research Network [J] . Osafo Charlotte, Raji Yemi R., Olanrewaju TimothyMamven ManmakArogundade FatiuAjayi SamuelUlasi IfeomaSalako BabatundePlange-Rhule JacobMengistu YewondwossenMcLigeyo S. O.Moturi GeorgeWinkler Cheryl A.Moxey-Mims Marva M.Rasooly Rebekah S.Kimmel PaulAdu DwomoaOjo AkinloluParekh Rulan S. Kidney international. . 2016,第1期

机译：Genomic approaches to the burden of kidney disease in Sub-Saharan Africa: the Human Heredity and Health in Africa (H3Africa) Kidney Disease Research Network
4. Using Socially Sensed Big Data to Model Patterns and Geographic Context of Human Activities in Cities =使用社会感知大数据对城市中人类行为的模式和地理上下文建模 [D] . Fu, Cheng. 2018

机译：Using Socially Sensed Big Data to Model Patterns and Geographic Context of Human Activities in Cities =使用社会感知大数据对城市中人类行为的模式和地理上下文建模
5. Hedgehog/notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung disease in mice and humans [O] . Kwok CKM, Lui VCH, Sham PC, 2011

机译：Hedgehog/notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung disease in mice and humans

NAD+ and mtRNA sensing drive human kidney diseases

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