Thigh circumference and risk of heart disease and premature death: prospective cohort study

摘要

STUDY QUESTION Is thigh size independently related to cardiovascular and coronary heart disease or premature death and is there a threshold for effect?SUMMARY ANSWER Smaller thigh size is associated with an increased risk of cardiovascular morbidity and early mortality independently of abdominal and general obesity and lifestyle and cardiovascular risk factors. There was a threshold effect, with a greatly increased risk of premature death associated with thigh size below around 60 cm.Participants and setting A random subset of 1436 men and 1380 women aged 35-65 participating in the Danish MONICA project.