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Prevalence of dyslipidemia and associated factors among the hypertensive rural chinese population.

机译:中国高血压农村人群血脂异常患病率及相关因素

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BACKGROUND: Dyslipidemia plays a crucial rule in the development of cardiovascular disease, which has become the leading cause of death in most developed countries as well as in developing countries. This study was designed to investigate the epidemiological features of dyslipidemia in rural adults with hypertension in China. METHODS: A cross-sectional survey was conducted during 2004-2006 through a cluster multistage sampling to a resident group of 6,412 individuals (2,805 men, 3,607 women) with hypertension, aged >/=35 years, in the countryside of Liaoning, China. Serum lipids levels were proposed by National Cholesterol Education Program Adult Treatment Panel III. RESULTS: Of the study population 34.4% had borderline high total cholesterol (TC), 16.9% had high TC, and 8.8% had low high-density lipoprotein cholesterol (HDL-C). The population with borderline high, high, and very high low-density lipoprotein cholesterol (LDL-C) was 15.7, 3.5, and 0.9%, respectively. In addition, 15.9% had borderline high triglycerides (TG), 17.8% had high TG and 2.0% had very high TG. After adjusting for independent variables, TC and TG had the same risk with fasting plasma glucose (FPG) and body mass index. Risk factors of TC and LDL-C were women, age and FPG. Mongolia nationality as a protective factor positively correlated with TC, LDL-C, and TG. Women, age, drinking, and classification of blood pressure were protective factors but Mongolia nationality was a risk factor for HDL-C. CONCLUSIONS: This study demonstrated that the prevalence of dyslipidemia was relatively high among rural hypertensive patients in China and there were many modifiable risk factors for dyslipidemia such as hypertension, weight, and impaired glucose metabolism. To prevent dyslipidemia and to reduce the increasing burden of cardiovascular disease in rural areas with the undeveloped economy of China, the first aim for us is to reduce these risk factors.
机译:背景:血脂异常在心血管疾病的发展中起着至关重要的作用,而心血管疾病已成为大多数发达国家和发展中国家的主要死亡原因。本研究旨在调查中国农村成年人高血压血脂异常的流行病学特征。方法:在2004-2006年期间,通过多阶段整群抽样对中国辽宁农村地区的居民人群进行了横断面调查,该居民人群为年龄≥35岁的6,412名高血压居民(2,805名男性,3,607名女性)。全国胆固醇教育计划成人治疗小组III提出了血脂水平。结果:在研究人群中,有34.4%的临界总胆固醇(TC),16.9%的较高TC和8.8%的高密度脂蛋白胆固醇(HDL-C)低。高,低和非常高的低密度脂蛋白胆固醇(LDL-C)的临界人群分别为15.7%,3.5%和0.9%。此外,边缘性高甘油三酯(TG)为15.9%,TG高为17.8%,TG非常高为2.0%。调整独立变量后,TC和TG的空腹血糖(FPG)和体重指数具有相同的风险。 TC和LDL-C的危险因素是女性,年龄和FPG。蒙古族作为保护因子与TC,LDL-C和TG正相关。妇女,年龄,饮酒和血压分类是保护因素,但蒙古族是HDL-C的危险因素。结论:这项研究表明,中国农村高血压患者的血脂异常患病率较高,并且有许多可改变的血脂异常危险因素,例如高血压,体重和葡萄糖代谢受损。为了预防血脂异常,并减轻中国经济欠发达地区农村地区心血管疾病的负担,我们的首要目标是减少这些危险因素。

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