Second cancers early post allogeneic transplant: The case of 'unrestrained' malignancy

摘要

The incidence of second malignancies following hematopoietic SCT (HSCT) is low, ~5%.1 The majority of these are hematological, with epithelial malignancies occurring at an incidence of 1-2% at 10-years post transplant, and increasing over time.1 Allogeneic transplant recipients have a 2-6 times higher risk of developing solid tumors when compared with the general population. Here, we present the case of a 34-year-old male patient who was diagnosed with a new carcinoma very soon after allogeneic HSCT. He had no significant past medical history when he presented with appendicitis.