Palladium-catalyzed cyanation reaction of aryl halides using K4[Fe(CN)6] as non-toxic source of cyanide under microwave irradiation

摘要

An efficient method for preparation of aryl nitriles - using [Pd{C6H2(CH2CH2 NH2)-(OMe)2,3,4} (n-Br)]2 complex as an efficient catalyst and K4[Fe(CN)6] as a green cyanide source-from aryl bromides, aryl iodides and aryl chlorides under microwave irradiation has been reported. This complex has been demonstrated to be an active and efficient catalyst for this reaction. Using a catalytic amount of this synthesized palladium complex in DMF at 130 °C led to production of the cyanoarenes in excellent yields in short reaction times.