Recyclable and reusable Pd(OAc)(2)/PPh3/PEG-2000 system for homocoupling reaction of arylboronic acids under air without base

摘要

A stable and efficient Pd(OAc)(2)/PPh3/PEG-2000 catalytic system for homocoupling of arylboronic acids has been developed. In the presence of Pd(OAc)(2) and PPh3, the homocoupling reaction of arylboronic acids was carried out smoothly in PEG-2000 at 70 degrees C under air without base to afford a variety of symmetric biaryls in good to excellent yields. The isolation of the products was readily performed by extraction with diethyl ether, and the Pd(OAc)(2)/PPh3/PEG-2000 system could be easily recycled and reused six times without significant loss of catalytic activity. Copyright (C) 2014 John Wiley & Sons, Ltd.