Synthesis of Functionalized Bicyclic Imines via Intramolecular Azide-Alkene 1,3-Dipolar Cycloaddition/Intramolecular Stork Alkylation Cascade Reaction

摘要

A cascade intramolecular azide-alkene 1,3-dipolar cycloaddition/Stork alkylation reaction has been developed for the synthesis of functionalized cyclic imines with a pyrroline and piperideine structures, employing readily available ω-azido-dienes.