Nimble micromanagement of macromolecules.

摘要

The shear enormity of the numbers defies comprehension, dwarfing even the most aggressive congressional proposal to bail out the economy. Eighty to 90% of all intracellular protein is degraded through the ubiquitin-proteasome pathway. Of these proteins, the proteasome degrades about 500,000 different "slowly degraded protein" (or SDPs) substrates per minute, per cell.