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AN 11-YEAR-OLD BOY DEVELOPED A GENERAL-ized erythematous macular rash 5 weeks prior to hospitalization. The rash resolved in 3 weeks but he then developed fevers and a sore on his inner left arm (Figure 1). The lesion was painful and red. One week prior to hospital admission, a complete blood cell count revealed a low white blood cell count of 3.6 X 10~3/uL with a normal hemoglobin concentration and platelet count. A sore throat was present and he complained of oral ulcers. On hospital admission, he was ill appearing and febrile (40癈), with marked oral ulceration. In addition to an eschar measuring 1.5 cm on his left upper arm with underlying induration (Figure 1). he had a tender lymph node in the nearby axilla. His laboratory test results showed a white blood cell count of 1.6 X 10~3/uL (12% band forms, 67% segmented neutrophils, 20% lymphocytes), a hemoglobin concentration of 9.4 g/dL, and a platelet count of 71X 10~3/uL. His fibrin split products were elevated and the fibrinogen level was falling.His serum ferritin level was 18 070 ng/mL (40 603 pmol/L). His C-reactive protein level was elevated at greater than 20 mg/dL, but surprisingly, his erythrocyte sedimentation rate was normal at 5 rnrn/h. His serum and urine electrolyte levels were consistent with syndrome-inappropriate antidiuretic hormone, and his uric acid and lactate dehydrogenase levels were elevated. Epstein-Barr virus testing was consistent with prior infection.
机译:一个11岁的男孩发达GENERAL-ized红斑的黄斑皮疹前5周住院治疗。然后他发达发烧,他内心的痛左臂(图1)。痛苦和损伤红色的。完整的血液细胞计数显示低白色血液细胞计数的3.6 X 10 ~ 3 / uL正常血红蛋白浓度和血小板计数。喉咙痛是口头的现在和他抱怨溃疡。appearing and febrile (40癈), with marked oral溃疡。左手上臂与底层1.5厘米硬化(图1)。他有一个温柔的淋巴结在附近的腋窝。显示白细胞计数1.6 X 10 ~ 3 / uL分段中性粒细胞乐队形式(12%,67%,20%淋巴细胞),血红蛋白浓度为9.4g / dL,血小板计数的71 x 10 ~ 3 / uL。纤维蛋白分离产品和升高纤维蛋白原水平下降。水平18岁070 ng / mL (40 603 pmol / L)。在更大的c反应蛋白水平升高比20 mg / dL,但令人惊讶的是,他的红细胞沉降速度是正常的在5 rnrn / h。血清和尿电解质水平符合syndrome-inappropriate抗利尿激素,和他的尿酸乳酸脱氢酶水平升高。巴尔病毒测试是一致的之前感染。

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