A 74-year-old white woman with lichen planus and hemoglobin 13Og/L was started on 100 mg of dapsone daily. Within 2 weeks she developed progressive fatigue, shortness of breath on exertion, yellowing of her skin, and dark urine. By the time she was assessed and admitted to hospital approximately 4 weeks later, her hemoglobin was 75g/L with elevated LDH, reticulocyte count, and indirect bilirubin. She was otherwise healthy and was not on any other medications. There was no family history of anemia or G6PD deficiency. The antiglobulin test was negative, and a G6PD test was not ordered. The dapsone was discontinued and she received 3 units of red blood cell concentrates. One week later she was seen by hematology. The hemoglobin, reticulocyte count, and indirect bilirubin had returned to normal. The original peripheral blood smear was unavailable but the current smear showed "bite" cells (see arrows in figure)
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机译：每天使用100毫克氨苯砜开始治疗一名74岁的白人女性，患有扁平苔藓和血红蛋白13Og / L。在2周内，她出现了进行性疲劳，劳累气短，皮肤发黄和尿液发黑。大约4周后，当她接受评估并入院时，她的血红蛋白为75 g / L，其中LDH升高，网织红细胞计数和间接胆红素升高。否则她很健康，没有其他任何药物。没有贫血或G6PD缺乏的家族史。抗球蛋白测试为阴性，没有下令进行G6PD测试。停用氨苯砜，她接受了3个单位的红细胞浓缩液。一周后，她被血液学检查。血红蛋白，网织红细胞计数和间接胆红素已恢复正常。最初的外周血涂片不可用，但当前的涂片显示“被咬”的细胞（参见图中的箭头）
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