Lack of evidence that saturated fat causes heart disease

摘要

From table 2 and the references of their systematic analysis, Micha and colleagues seem to recommend replacing saturated fatty acids (SFAs) with polyunsaturated fatty acids (PUFAs) to lowerthe risk of cardiovascular disease.1 As support they referto the joint WHO/FAO expert consultation from 2003, in which the evidence came from an American Heart Association consensus report. The only argument in that report came from the Nurses' Health Study, but from the tables in that study it seems that, after multivariate adjustment, including various types of dietary fats, the relative risk of coronary heart disease did not differ significantly between the different levels of dietary SFA intake.