Collaboration between academics and industry in clinical trials

摘要

Study question What are the roles of academic authors, funders, and contract research organisations in industry funded trials of vaccines, drugs, and devices? Methods This was a cross sectional analysis of trial publications and survey of lead academic authors. It included the most recent 200 phase III and IV trials of vaccines, drugs, and devices with full industry funding and at least one academic author, published in one of the top seven high impact general medical journals (New England Journal of Medicine, Lancet, JAMA, BMJ, Annals of Internal Medicine, JAMA Internal Medicine, and PLoS Medicine). The reported roles of academic authors, funders, and contract research organisations were determined, and lead academic authors were surveyed about experiences with the industry funder collaboration.