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Racial differences in primary care opioid risk reduction strategies.

机译:初级保健阿片类药物风险降低策略中的种族差异。

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PURPOSE: Racial disparities in treating pain with opioids are widely reported; however, differences in use of recommended strategies to reduce the risk of opioid misuse by race/ethnicity have not been evaluated. METHODS: In a retrospective cohort of black and white patients with chronic noncancer pain prescribed opioid analgesics for at least 3 months, we assessed physicians' use of 3 opioid risk reduction strategies: (1) urine drug testing, (2) regular office visits (at least 1 visit per 6 months on opioids and within 30 days of an opioid change), and (3) restricted early opioid refills (receipt of a refill >1 week early less than twice). Nonlinear mixed effect regression models accounted for clustering within physician and adjusted additively for demographics, substance abuse, mental health and medical comorbidities, health care factors, and practice site. RESULTS: Of the 1,612 patients studied, 62.1% were black. Black patients were more likely than white patients to receive urine drug testing (10.4% vs 4.1%), regular office visits (56.4% vs 39.0%), and restricted early refills (79.4% vs 72.0%) (P <.001 for each). In fully adjusted models, black patients had significantly higher odds than their white counterparts of receiving regular office visits (odds ratio = 1.51; 95% confidence interval, 1.06-2.14) and restricted early refills (odds ratio = 1.55; 95% confidence interval, 1.03-2.32), but not urine drug testing (odds ratio = 1.41; 95% confidence interval, 0.78-2.54). CONCLUSIONS: In this cohort of primary care patients receiving opioid analgesics on a long-term basis, use of risk reduction strategies was very limited overall; however, black patients were more likely than white patients to receive 2 of 3 guideline-recommended strategies. These data raise questions about lax monitoring, especially for white patients taking opioids long term.
机译:目的:阿片类药物治疗疼痛的种族差异被广泛报道;但是,尚未评估使用推荐策略减少种族/族裔滥用阿片类药物的风险的差异。方法:在一项回顾性队列研究中,对患有慢性非癌性疼痛且开具阿片类镇痛药的黑人和白人患者进行了至少3个月的回顾性研究,我们评估了医生使用的3种降低阿片类药物风险的策略:(1)尿液药物检测,(2)定期就诊(至少每6个月接受一次阿片类药物治疗,并在阿片类药物变化发生后30天内进行至少3次拜访),以及(3)限制早期阿片类药物补充治疗(接受补充治疗的时间> 1周且少于两次)。非线性混合效应回归模型解释了医师内部的聚类情况,并针对人口统计学,药物滥用,心理健康和医疗合并症,医疗保健因素以及执业地点进行了调整。结果:在研究的1,612名患者中,有62.1%是黑人。黑人患者比白人患者更有可能接受尿液测试(10.4%vs 4.1%),常规办公室就诊(56.4%vs 39.0%)和早期限用笔芯(79.4%vs 72.0%)(每个P <.001 )。在完全调整后的模型中,黑人患者接受常规办公室就诊的几率显着高于白人(赔率= 1.51; 95%置信区间,1.06-2.14)和受限制的早期补充(赔率= 1.55; 95%置信区间, 1.03-2.32),但不进行尿液药物测试(赔率= 1.41; 95%置信区间0.78-2.54)。结论:在这一长期接受阿片类镇痛药的基层医疗患者队列中,降低风险的策略总体上非常有限。但是,黑人患者比白人患者更有可能接受3种指南推荐策略中的2种。这些数据引发了有关监测不严的问题,特别是对于长期服用阿片类药物的白人患者。

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