Use of a reduced (4-dose) vaccine schedule for postexposure prophylaxis to prevent human rabies-recommendations of the Advisory Committee on Immunization Practice.

摘要

This report summarizes new recommendations and updates previous recommendations of the Advisory Committee on Immunization Practices (ACIP) for postexposure prophylaxis (PEP) to prevent human rabies (Centers for Disease Control and Prevention. Human rabies prevention-United States, 2008: recommendations of the Advisory Committee on Immunization Practices. MMWRMorb Mortal Wkly Rep. 2008; 57:1-28). Previously, ACIP recommended a 5-dose rabies vaccination regimen with human diploid cell vaccine (HDCV) or purified chick embryo cell vaccine (PCECV). These new recommendations reduce the number of vaccine doses to 4.