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首页> 外文期刊>Journal of cardiovascular electrophysiology >Incidence and clinical impact of early recurrence of atrial tachyarrhythmia after surgical ablation for atrial fibrillation
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Incidence and clinical impact of early recurrence of atrial tachyarrhythmia after surgical ablation for atrial fibrillation

机译:心房颤动术后心房心律失常早期复发的发病率和临床影响

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Background Atrial tachyarrhythmias (ATAs) are common within the 3-month blanking period after catheter ablation of atrial fibrillation (AF). However, little evidence is available regarding the current guidelines on the blanking period after surgical AF ablation. We investigate the incidence and significance of early recurrence of atrial tachyarrhythmia (ERAT) and evaluate the optimal blanking period after surgical AF ablation. Methods Data from 259 patients who underwent surgical AF ablation from 2009 to 2016 were collected. ERAT was defined as documented ATA episodes lasting for 30 s. A multivariate Cox proportional hazard model was constructed to evaluate the role of ERAT as a predictor of late recurrences (LR) for AF. Results In total, 127 patients (49.0%) experienced their last episodes of ERAT during the first (n = 65), second (n = 14), or third (n = 48) month of the 3-month blanking period (p < .001). One year freedom from ATAs was 97.8% in patients without ERAT compared with 95.4%, 64.3%, and 8.3% in patients with ERAT in the first, second, and third months after the index procedure, respectively (p < .001). Hazard ratios of LR according to the timing of the last episode of ERAT first, second, and third months after the procedure were 2.84, 16.70, and 119.75, respectively. Conclusions The ERAT occurred in 49.0% of patients within the first 3 months after surgical ablation. The occurrence of ERAT within 3 months after surgical AF ablation was a significant independent predictor of LR. Hence, the currently accepted 3-month blanking period may be considered for redefining in patients with AF surgical ablation.
机译:背景心房颤动(AF)导管消融术后3个月内,房性快速心律失常(ATA)很常见。然而,目前关于房颤手术消融后的空白期的指南几乎没有证据。我们研究房性快速心律失常(ERAT)早期复发的发生率和意义,并评估手术房颤消融术后的最佳消隐期。方法收集2009年至2016年259例房颤手术消融患者的资料。ERAT被定义为持续30秒的有记录的ATA发作。建立了多变量Cox比例风险模型,以评估ERAT作为房颤晚期复发(LR)预测因子的作用。结果总共有127名患者(49.0%)在3个月空白期的第一个月(n=65)、第二个月(n=14)或第三个月(n=48)经历了最后一次ERAT发作(p<0.001)。无ERAT的患者一年内无ATAs发生率为97.8%,而在指数程序后的第一个月、第二个月和第三个月,有ERAT的患者一年内无ATAs发生率分别为95.4%、64.3%和8.3%(p<0.001)。根据术后第一、第二和第三个月ERAT最后一次发作的时间,LR的危险比分别为2.84、16.70和119.75。结论49.0%的患者术后3个月内发生ERAT。术后3个月内发生ERAT是LR的一个重要独立预测因子。因此,目前可接受的3个月消隐期可被考虑用于房颤手术消融患者的重新定义。

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