A multicenter phase II study of pazopanib in patients with advanced gastrointestinal stromal tumors (GIST) following failure of at least imatinib and sunitinib.

K N Ganjoo; V M Villalobos; A Kamaya; G A Fisher; J E Butrynski; J A Morgan; A J Wagner; D DAdamo; A McMillan; G D Demetri; S George

首页> 外文期刊>Annals of oncology: official journal of the European Society for Medical Oncology >A multicenter phase II study of pazopanib in patients with advanced gastrointestinal stromal tumors (GIST) following failure of at least imatinib and sunitinib.

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A multicenter phase II study of pazopanib in patients with advanced gastrointestinal stromal tumors (GIST) following failure of at least imatinib and sunitinib.

机译：多唑帕尼对至少伊马替尼和舒尼替尼治疗失败的晚期胃肠道间质瘤（GIST）患者的多中心II期研究。

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Pazopanib was reasonably well tolerated with no unexpected toxicities. Pazopanib as a single agent has marginal activity in unselected heavily pretreated patients with advanced GIST.

机译：帕唑帕尼的耐受性相当好，没有意外的毒性。帕唑帕尼作为单一药物在未经选择的重度GIST严重治疗前患者中仅具有少量活性。

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《Annals of oncology: official journal of the European Society for Medical Oncology 》 |2014年第1期| 共5页
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K N Ganjoo; V M Villalobos; A Kamaya; G A Fisher; J E Butrynski; J A Morgan; A J Wagner; D DAdamo; A McMillan; G D Demetri; S George;
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正文语种 eng
中图分类肿瘤学 ;
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1. A multicenter phase II study of pazopanib in patients with advanced gastrointestinal stromal tumors (GIST) following failure of at least imatinib and sunitinib. [J] . K N Ganjoo, V M Villalobos, A Kamaya, Annals of oncology: official journal of the European Society for Medical Oncology . 2014 ,第1期

机译：多唑帕尼对至少伊马替尼和舒尼替尼治疗失败的晚期胃肠道间质瘤（GIST）患者的多中心II期研究。
2. Prospective multicentric randomized phase III study of imatinib in patients with advanced gastrointestinal stromal tumors comparing interruption versus continuation of treatment beyond 1 year: the French Sarcoma Group. [J] . Blay JY, Le-Cesne A, Ray-Coquard I, Journal of Clinical Oncology . 2007 ,第9期

机译：伊马替尼在晚期胃肠道间质瘤患者中进行的前瞻性多中心随机III期研究，比较中断治疗与持续治疗超过1年的情况：法国肉瘤组织。
3. Imatinib efficacy by tumor genotype in Korean patients with advanced gastrointestinal stromal tumors (GIST): The Korean GIST Study Group (KGSG) study [J] . KangH.J., RyuM.-H., KimK.-M., Acta oncologica. . 2012 ,第4期

机译：韩国晚期胃肠道间质瘤（GIST）患者的肿瘤基因型依马替尼疗效：韩国GIST研究小组（KGSG）研究
4. International classifications of gastrointestinal stromal tumor: a clue for adjuvant imatinib treatment [C] . Tzen Chin-Yuan International Gastric Cancer Congress . 2011

机译：胃肠道间质瘤的国际分类：佐剂伊马替尼治疗的线索
5. Molecular mechanisms of response in gastrointestinal stromal tumors treated with imatinib mesylate [D] . McAuliffe, John Christopher 2007

机译：甲磺酸伊马替尼治疗胃肠道间质瘤的分子机制
6. A multicenter phase II study of pazopanib in patients with advanced gastrointestinal stromal tumors (GIST) following failure of at least imatinib and sunitinib [O] . K. N. Ganjoo, V. M. Villalobos, A. Kamaya, -1

机译：多唑帕尼对至少伊马替尼和舒尼替尼治疗失败的晚期胃肠道间质瘤（GIST）患者的多中心II期研究
7. Imatinib plus low-dose doxorubicin in patients with advanced gastrointestinal stromal tumors refractory to high-dose imatinib: A phase I-II study by the Spanish group for research on sarcomas [O] . Maurel, Joan, Martins, Ana Sofia, Álava, Enrique de 2012

机译：伊马替尼加小剂量阿霉素用于难治性大剂量伊马替尼的晚期胃肠道间质瘤患者：西班牙小组I-II期研究，用于肉瘤研究
8. Report on the Relative Efficacy of Oral Cancer Therapy for Medicare Beneficiaries Versus Currently Covered Therapy: Part 2, Imatinib for Gastrointestinal Stromal Tumors (GIST) [R] . Abernethy, A. P., McCrory, D. C. 2005

机译：关于口服癌疗法对医疗保险受益人与目前报道疗法的相对疗效的报告：第2部分，伊马替尼治疗胃肠道间质瘤（GIsT）

A multicenter phase II study of pazopanib in patients with advanced gastrointestinal stromal tumors (GIST) following failure of at least imatinib and sunitinib.

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