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The ESMO guidelines working group would like to publish the following corrections to manuscripts published in 2012/2013

机译:ESMO准则工作组希望对2012/2013年出版的手稿发表以下更正

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Ann Oncol (2012) 23 (suppl 7): vii33-vii40. In the section on Treatment in Stage IV, in the second paragraph it is stated: "A recent phase III trial using a combination of 5-FU, irinotecan and oxaliplatin (FOLFIRINOX) has shown a response rate of 31.6%, a median survival of 11.1 months (hazard ratio 0.57, 95% confidence interval 0.45 -0.73), and 1-year survival rate of 48.4% in the FOLFIRINOX arm [29]. FOLFIRINOX also delayed deterioration of quality of life. In this trial, patients >75 years were excluded and eligibility was restricted to PS 0 and 1.60% of patients had cancers of the body and tail of pancreas." The last sentence of this extract should read: "In this trial, patients >75 years were excluded and eligibility was restricted to PS 0 and 58.7% of patients had cancers of the body and tail of pancreas." Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up Ann Oncol (2012) 23 (suppl 7): vii65-vii71. In the section on Management of Metastatic Disease, under the heading "First-line treatment for patients with prognosis" should read "First-line treatment for patients with poor prognosis". Figure 1. The following corrections to levels of evidences and grades of recommendations should be noted: First-line treatment: Clear-cell histology: Good/intermediate prognosis: Bevacizumab + interferon-a (IA) First-line treatment: Clear-cell histology: Good/intermediate prognosis: Pazopanib (IIB) First-line treatment: Clear-cell histology: Poor prognosis: Temsirolimus (IB) Figure 2. The following corrections to levels of evidences and grades of recommendations should be noted: Second line treatment: Previous treatment with a VEGF(Rs)-pathway inhibitor: Axitinib (IB)
机译:Ann Oncol(2012)23(suppl 7):vii33-vii40。在第IV阶段的治疗部分中,第二段指出:“最近使用5-FU,伊立替康和奥沙利铂(FOLFIRINOX)组合进行的III期试验显示,其缓解率为31.6%,中位生存期为FOLFIRINOX组11.1个月(危险比0.57,95%置信区间0.45 -0.73)和1年生存率48.4%[29]。FOLFIRINOX还延缓了生活质量的恶化,在该试验中,> 75岁的患者排除在外,资格仅限于PS 0,1.60%的患者患有胰腺和尾巴癌。”该摘录的最后一句应为:“在该试验中,年龄> 75岁的患者被排除在外,并且资格仅限于PS 0,并且58.7%的患者患有胰腺和尾巴癌。”肾细胞癌:《 ESMO诊断,治疗和随访临床实践指南》,Ann Oncol(2012)23(suppl 7):vii65-vii71。在“转移性疾病的治疗”部分中,在“预后不良的一线治疗”标题下应阅读“预后不良的一线治疗”。图1.应注意以下对证据水平和建议等级的更正:一线治疗:透明细胞组织学:良好/中度预后:贝伐单抗+干扰素-a(IA)一线治疗:透明细胞组织学:良好/中期预后:Pazopanib(IIB)一线治疗:透明细胞组织学:不良预后:Temsirolimus(IB)图2。应注意以下证据水平和建议等级的更正:二线治疗:上一VEGF(Rs)-途径抑制剂:Axitinib(IB)治疗

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