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Error mechanisms of the oscillometric fixed-ratio blood pressure measurement method

机译:示波法固定比例血压测量方法的误差机理

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摘要

The oscillometric fixed-ratio method is widely employed for non-invasive measurement of systolic and diastolic pressures (SP and DP) but is heuristic and prone to error. We investigated the accuracy of this method using an established mathematical model of oscillometry. First, to determine which factors materially affect the errors of the method, we applied a thorough parametric sensitivity analysis to the model. Then, to assess the impact of the significant parameters, we examined the errors over a physiologically relevant range of those parameters. The main findings of this model-based error analysis of the fixed-ratio method are that: (1) SP and DP errors drastically increase as the brachial artery stiffens over the zero trans-mural pressure regime; (2) SP and DP become overestimated and underestimated, respectively, as pulse pressure (PP) declines; (3) the impact of PP on SP and DP errors is more obvious as the brachial artery stiffens over the zero trans-mural pressure regime; and (4) SP and DP errors can be as large as 58 mmHg. Our final and main contribution is a comprehensive explanation of the mechanisms for these errors. This study may have important implications when using the fixed-ratio method, particularly in subjects with arterial disease.
机译:示波固定比率法被广泛用于收缩压和舒张压(SP和DP)的非侵入性测量,但是它具有启发性并且容易出错。我们使用建立的示波法数学模型研究了该方法的准确性。首先,为了确定哪些因素会严重影响该方法的误差,我们对该模型进行了全面的参数敏感性分析。然后,为了评估重要参数的影响,我们检查了那些参数在生理上相关范围内的误差。这种基于模型的固定比率方法误差分析的主要发现是:(1)SP和DP误差随着臂动脉在零跨壁压力范围内变硬而急剧增加; (2)随着脉冲压力(PP)的下降,SP和DP分别被高估和低估; (3)当肱动脉在跨壁压力为零时变硬时,PP对SP和DP误差的影响更加明显。 (4)SP和DP误差可能高达58 mmHg。我们的最终也是主要的贡献是对这些错误的机制的全面解释。当使用固定比率方法时,该研究可能具有重要意义,尤其是在患有动脉疾病的受试者中。

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