The short-term effects of resistance training on quality of life, cancer related fatigue, body composition, and physical function in men with advanced and metastatic prostate cancer receiving androgen deprivation therapy: a pilot study

摘要

Background: Prostate cancer, a disease of aging, is the most common cancer for men living in the developed world. Androgen Deprivation Therapy is effective at slowing the progression of prostate cancer cell growth; however, a myriad of musculoskeletal side effects can result from the long-term use. Resistance exercise training has been shown to have a positive effect on quality of life and physical function in cancer survivors. Objective: To measure the short-term effects of an eight-week resistance training program utilizing low cost non-machine based resistive exercise in men with advanced and metastatic prostate cancer. Major Finding: A significant impact on body composition, physical function, and emotional well-being was found after 8 weeks of training. Conclusions: Results suggest that low-cost resistance exercise training conducted in a group setting is effective in improving strength, balance and health-related quality of life in prostate cancer survivors with advanced and metastatic disease.