The effect of medroxyprogesterone acetate on behavioural responses of captive female hamadryas baboons (Papio hamadryas)

摘要

Female hormonal contraception is considered here as an alternative to vasectomy for population control in social groups of captive hamadryas baboons (Papio hamadryas). While female hormonal contraceptive methods have been successful, behavioural effects of such agents represent a potential welfare concern. This study examined the effect of medroxyprogesterone acetate (MPA; 3.5mg/kg) on perineal tumescence and behaviour in three social groups (total of 3 males, 22 females) of captive hamadryas baboons. The agent had little effect on social interactions such as grooming relationships, aggression and affiliation (all P >0.05), but did cause a reduction in sexual behaviour (P <0.001). Females-mounting-females and females receiving mounting was decreased during MPA treatment compared with the minimal tumescence phase (P <0.001). Age strongly influenced the contraceptive's duration: there was a significant correlation between age and latency of return to oestrus post-MPA (r =0.832, P <0.001) with the latency increasing by 2.61 days per year of age on average. Age also influenced the frequency of behaviours such as affiliation and aggression (P <0.001 and P =0.044, respectively). The absence of adverse behavioural effects further supports the use of MPA in the hamadryas baboon, and its potential use in other non-human primates.