Synthesis of Potential Biologically Active Compounds Based on Aryloxy- and Arylaminopropanehydrazides

摘要

New derivatives of a number of aryloxy and arylaminopropanehydrazides were synthesized. Their heterocyclization under the action of carbon disulfide and potassium hydroxide and subsequent alkylation of the resulting 2-thioxo-1,3,4-oxadiazole ring, the corresponding S-substituted products were obtained. The reaction of the starting hydrazides with arylaldehydes and pentane-2,4-dione afforded theirN '-arylidene and N '-(4-oxopentan-2-ylidene) derivatives. In preliminary laboratory tests, the synthesized compounds showed a pronounced stimulating effect on plant growth. Their activity was 44-95% compared with heteroauxin.