Association, Relationship of Various Caronary Artery Disease Risk Factors with Age, Gender and Different Obesity Indices among the South Indian Adult Subjects: A Regression Analysis

摘要

The Overall aim of this study was to assess the association and relationships of various anthropometry measures, metabolic characters and Adipokines in overweight, obese adult subjects with the risk for Coronary artery disease. In the present study atotal of 490 subjects; male (228) and females (262) of aged 20-59 years were included. Subjects in different age groups were: 20-39 years 223 (110 males and 113 females) and 40-59 years 267 (118 males and 149 females). Height, weight, waist, hip circumferences and Blood pressure measured with calibrated instrument from all participants. Blood sample was collected; Serum was used to measure the following parameters glucose, insulin, and lipid profile, Leptin and Adiponectin. Age, sex adjusted and the three different obesity indices such as BMI, Waist circumference and Waist to hip ratio was considered as dependent factor, other characteristics were taken as an independent factor then Spearman correlation coefficients was used to find relationships between each of independent with dependent characteristics. The results of the present study showed good agreementamong the different obesity indices. BMI was stronger and positively correlated with waist circumference (r= 0.83) as well as with waist to hip ratio (r= 0.72). The Waist circumference was also stronger and positively correlated with waist to hip ratio (r= 0.64). The study also showed that the Systolic BP, Diastolic BP, Fasting blood glucose, Insulin level and Insulin resistance were positively correlated with BMI, waist circumference and waist to hip ratio of the study subjects. The Total cholesterol,Triglycerides and LDL-Cholesterol levels were also positively correlated with BMI, waist circumference and waist to hip ratio but the HDL-Cholesterol level was negatively correlated with BMI, waist circumference and waist to hip ratio of the study subjects. The levels of Leptin was positively correlated with BMI, waist circumference and waist to hip ratio but the Adiponectin level was negatively correlated with BMI, waist circumference and waist to hip ratio of the study subjects.