Epicardial Fat Thickness and its Association as a Risk Factor for Coronary Artery Disease

摘要

Background of study aims and objective:Epicardial fat thickness is a novel parameter for predicting outcome and assessment of severity of coronary artery disease. Our present study aims to establish an association between epicardial fat thickness and coronary artery disease. Materials & Methods: Patients of suspected CAD underwent coronary angiography. 100 subjects proven as confirmed cases were included in the study. Routine clinical examination, risk factor profile and anthropometric variables were also done. Severity of CAD was assessed using Gensini Score. Epicardial fat thickness was measured using 2D ECHO. For comparative analysis, 50 healthy individuals were also included in the study. Results: Epicardial fat thickness was significantly higher in cases (7.53 ± 1.79 mm) than controls (4.24 ± 1.09 mm). Female sex, hypertension, dyslipidemia, obesity were observed to affect EFT significantly. No difference in mean EFT was observed with age, diabetes, smoking, ECG changes and arterial territory involvement. BMI and Gensini scores both showed strong positive correlation with epicardial fat thickness. Conclusion: Epicardial fat thickness is associated and linearly correlates with onset and severity of CAD.