Mechanistic Study of Electrical Field Flow Fractionation. 1. Nature of the Internal Field

摘要

Experimental results indicate that the electric field governing retention in the electrical field-flow fractionation (FFF) experiment is very sensitive to experimental parameters such as the flow rate and carrier conductivity. In this paper, the first of a two-part study on the mechanics of electrical FFF, we present an electrical model of the channel and characterize the dependence of many of the system parameters. Understanding the nature of the electric field in the channel is essential for using electrical FFF as separation tool as well as a physical characterization technique where electrophoretic mobility and particle size are estimated.