...
首页> 外文期刊>Analytical chemistry >RELAXATION OF RANDOMNESS IN TWO-DIMENSIONAL STATISTICAL MODEL OF OVERLAP - THEORY AND VERIFICATION
【24h】

RELAXATION OF RANDOMNESS IN TWO-DIMENSIONAL STATISTICAL MODEL OF OVERLAP - THEORY AND VERIFICATION

机译:二维重叠统计模型中的随机性放松-理论与验证。

获取原文
获取原文并翻译 | 示例
           

摘要

An equation for the expected number of spots in a two-dimensional (2-D) separation containing randomly distributed single-component spots (SCSs) was modified to predict the expected number of spots when the local density of SCSs is random but varies continuously throughout the separation. The modified equation was expressed by a double integral, whose value depends on the mean number of SCSs, the average saturation of the separation, and a dimensionless frequency proportional to SCS density. This equation is much more useful for interpretation of separations than its predecessor, because SCSs in 2-D separations rarely are distributed with constant density but rather with variable density. The modified equation was verified by two types of computer simulations, in which SCSs were represented alternatively by constant-diameter circles and by bi-Gaussians having circular contours and exponentially distributed amplitudes, An excellent agreement between simulation and theory was obtained over a wide range of saturations when SCSs were represented by circles; a good agreement was obtained for saturations less than a critical threshold when SCSs were represented by bi-Gaussians. The equation also was used to predict the number of SCSs in separations of low saturation, in which SCSs were represented by either 30 or 250 bi-Gaussians. This prediction required estimating frequencies from the coordinates of maxima, and two procedures for this estimation were proposed and tested. The predictions on average were very good, as long as the saturation was below a critical threshold. The modified theory was shown to be insensitive to arbitrary definition of the separation's borders, which has practical importance.
机译:修改了包含随机分布的单组分斑点(SCS)的二维(2-D)分离中预期斑点数的方程,以预测SCS的局部密度为随机但在整个过程中连续变化的预期斑点数分离。修改后的方程式由一个双积分表示,其值取决于SCS的平均数量,分离的平均饱和度以及与SCS密度成比例的无量纲频率。该方程比其前身对分离的解释更为有用,因为二维分离中的SCS很少以恒定密度分布,而是以可变密度分布。修改后的方程通过两种类型的计算机仿真进行了验证,其中,SCS分别由等直径圆和具有圆轮廓且幅度呈指数分布的双高斯交替表示,在较大范围内的仿真与理论之间取得了很好的一致性。用圆圈表示SCS时的饱和度;当以双高斯表示SCS时,对于饱和度小于临界阈值的饱和度,可以获得良好的一致性。该方程还用于预测低饱和度分离中的SCS数量,其中SCS用30或250个双高斯表示。该预测需要从最大值坐标估计频率,并且提出并测试了用于此估计的两个过程。只要饱和度低于临界阈值,平均预测就非常好。事实表明,修改后的理论对分隔边界的任意定义不敏感,这具有实际意义。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号