Automated Monte-Carlo re-calculation of proton therapy plans using GEANT4/GATE: implementation and comparison to plan-specific quality assurance measurements

摘要

Objectives: Software re-calculation of proton pencil beam scanning plans provides a method of verifying treatment planning system (TPS) dose calculations prior to patient treatment. This study describes the implementation of AuroMC, a GEANT4 v10.3.3/GATE v8.1 (GATE-RTioN v1.0)-based Monte-Carlo (MC) system for automated plan re-calculation, and presents verification results for 153 patients (730 fields) planned within year one of the proton service at The Christie NHS Foundation Trust.