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Smartphone-based apparatus for measuring upconversion luminescence lifetimes

机译:基于智能手机的测量装置的寿命寿命

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Luminescence lifetime detection plays an important role in time-resolved detection and research. However, the traditional instruments always require expensive detectors such as time-correlated single photon counter or streak camera. Herein, a low-cost and miniaturized apparatus for measuring upconversion luminescence lifetimes was developed by using a smartphone equipped with a 980 nm CW laser and a motor. When the motor was driving the sample circling at a high linear velocity, the excited sample would emit a luminescence arc, which could be photographed by the phone camera. The rotating rate could be measured by a tuner APP and then used for transferring arc length to delay times. By analyzing the grayscale distribution of the luminescence arc, the luminescence decay curve was obtained, which was then used for exponential fit and calculating lifetimes. The images captured by different smartphones revealed similar lifetime values, suggesting a wide universality of this method. The whole system was not only remarkably cheaper but also more miniaturized than traditional instruments for measuring luminescence lifetimes, indicating the promising applications in point of care testing for time-resolved luminescence detection for bioanalysis and disease diagnosis. (C) 2018 Elsevier B.V. All rights reserved.
机译:发光寿命检测在时间解决的检测和研究中起着重要作用。然而,传统的仪器总是需要昂贵的探测器,例如时间相关的单光子计数器或连杆相机。这里,通过使用配备有980nm CW激光器和电动机的智能手机开发了一种用于测量上变频发光寿命的低成本和小型化装置。当电动机以高线速速度驱动样品时,激发的样品会发出发光弧,这可以通过电话机拍摄。旋转速率可以通过调谐器应用来测量,然后用于将电弧长度传送到延迟时间。通过分析发光弧的灰度分布,获得了发光衰减曲线,然后用于指数配合和计算寿命。由不同智能手机捕获的图像显示出类似的寿命值,表明这种方法的广泛普遍性。整个系统不仅比传统的仪器更便宜,而且比传统的测量发光仪器更具小型化,表明在治疗生物分析和疾病诊断的时间分辨发光检测点中有前途的应用。 (c)2018 Elsevier B.v.保留所有权利。

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