Assessment of body cell mass at bedside in critically ill patients

摘要

For the past two decades, bioelectrical impedance analysis (BIA), an easy and noninvasive technology available at bedside, has been widely used to assess water compartments or FFM in patients without marked fluid distribution disturbances (7, 21, 42). However, regression equations for FFM or BCM estimation derived from single- or multiple-frequency BIA are population specific and yield misleading results for patients with fluid overload (17, 19, 21, 32, 39). In addition, the use of single-frequency, 50-kHz BIA is not appropriate to estimate body water or FFM when critical illness is causing compartmental flux (17, 26). Multiple-frequency BIA, although less accurate in critical illness, remains the only bedside technique for estimating water compartments (26, 32, 43, 48). Therefore, combining multiple-frequency BIA with FM, FFM, and Mo determinations may be an alternative method of estimating BCM in critically ill patients.