Direct nucleophilic reactions of aldehyde over secondary-amine immobilised FSM-16 catalyst

摘要

Secondary-amine immobilised FSM-16 and 5i02 were developed as effective catalysts for nucleophilic reactions of aldehyde. These catalysts act as active and reusable heterogeneous catalysts for the direct conjugate addition of unmodified aldehydes to vinylketones as well as for the self-aldol condensation of unmodified aldehydes. Secondary-amine immobilised silica in ionic liquid, [bmim]PF_6, was efficiently recycled more than eight times for self-aldol condensation of various aldehydes. The present system can be regarded as a novel heterogeneous catalysis for a practical and environmentally friendly C-C formation reaction.