心拍間隔情報を用いた新生仔ラットの脳障害判別法に関する研究

摘要

This paper proposes a new method of the distiniction method of the newborn rat brain damageusing heart beat interval information. We investigated the factor related to the brain damage by using thehypoxic-ischemic encephalopathy model of the newborn rat. From the experiment results, significant factorswere the coefficient of variation of the heartbeat intervals and the histogram information. The proposeddistinction method succeeded in 21 distinctions in 25 newborn rats (brain non-damage 16 and brain damage 9).This paper shows that it becomes possible to judge the brain damage of an actual embryo by using the heartbeatinterval information at the early stage.