The management of older adults with a low eGFR: moving toward an individualized approach.

摘要

In the general population, approximately 38% of adults 70 years or older have an estimated glomerular filtration rate (eGFR) less than 60 mL/min/1.73 m~2; most have moderate reductions in eGFR in the 30- to 59-mL/min/1 .73 m2 range. Some have argued that such moderate reductions in eGFR can occur as the result of normal aging and should not be equated with chronic kidney disease (CKD) in the absence of other abnormalities. Others note that reductions in eGFR in the elderly may reflect the high prevalence of kidney disease risk factors at older ages and should not necessarily be considered normal simply because they are common.