Anti-obesity Effect of Burdock Tea in Healthy Japanese: A Randomized, Double-blind, Placebo-controlled Study

摘要

Objectives: The objective of this study is to examine how the ingestion of Burdock (Arctium lappa L.) tea, "Baisen-GOBOUCHA" ("BG") containing inulin and chlorogenic acid contributes to an anti-obesity effect. Methods: A randomized, placebo-controlled, double-blind study was conducted to elucidate an anti-obesity effect of the tea containing inulin and chlorogenic acid. In this study we measured the visceral fat area, subcutaneous fat area, Body mass index (BMI), body weight, and body fat percentage as the primary outcome. We also evaluated the circumference of body parts (the waist, hip, upper arm, and upper leg) as a secondary endpoint. Furthermore, adverse effects were collected by means of a written questionnaire during the study. Results: From all of 72 applicants, 29 were eliminated due to not meeting inclusion criteria. The 43 subjects were randomly assigned to an intervention group and made a start with ingestion. 5 subjects were withdrawn due to business or fever, and the remaining 38 subjects completed the study. Thus, data obtained with 38 subjects (BG:18，