Additional effect size measures helpful in understanding lithium and valproate trial results.

摘要

To the Editor: The article by Oquendo et al. (1) in the October 2011 issue of the Journal deserves commendation for tackling one of the preeminent questions in psychiatry: whether certain psychiatric medications help to reduce suicidal behaviors. Oquendo and colleagues' randomized controlled trial was foresightedly conceived and initiated more than a decade ago, and I applaud the efforts of both the research staff and the patients (some of whom agreed to receive double-blind medication for more than 2 years!) involved in this important study.