Harnessing N-Methyl-d-Aspartate Receptors for New Treatment Development in Psychiatry: Positive Lessons From Negative Studies.

摘要

Social anxiety disorder is a common psychiatric condition associated with significant distress and restriction of activity. Cognitive-behavioral therapy (CBT) is a mainstay treatment for social anxiety disorder. While effective overall, CBT requires an extensive time commitment and is associated with significant nonre-sponse and relapse rates. In an article in this issue, Hofmann et al. (1) address the critical issue of whether the effectiveness of CBT can be enhanced with simultaneous pharmacological treatment.