Carpal Tunnel Syndrome Pathophysiology: Role of Subsynovial Connective Tissue

摘要

Carpal tunnel syndrome (CTS) is a very common pathology that can be secondary to a great number of conditions.1"3 However, the most common diagnosis for CTS is idiopathic. It is accepted that chronic increase in pressure within the carpal tunnel is responsible for median nerve ischemia and subsequent segmental demyelination,4'5 but the exact pathophysiology leading to this pressure increase remains unknown.When conservative treatment has failed, surgical division of the carpal transverse ligament (CTL) is considered. However surgical treatment gives excellent results in only 75% of the cases, leaving the remaining 25% with less satisfactory results.