Second-line HIV Treatment in Ugandan Children: Favorable Outcomes and No Protease Inhibitor Resistance

Boerma Ragna S.; Kityo Cissy; Boender T. Sonia; Kaudha Elizabeth; Kayiwa Joshua; Musiime Victor; Mukuye Andrew; Kiconco Mary; Nankya Immaculate; Nakatudde Lilian; Mugyenyi Peter N.; van Hensbroek Michael Boele; de Wit Tobias F. Rinke; Sigaloff Kim C. E.; Calis Job C. J.

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Second-line HIV Treatment in Ugandan Children: Favorable Outcomes and No Protease Inhibitor Resistance

机译：乌干达儿童的二线艾滋病毒治疗：有利的结果和蛋白酶抑制剂抗性

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Background: Data on pediatric second-line antiretroviral treatment (ART) outcomes are scarce, but essential to evaluate second-line and design third-line regimens.

机译：背景：关于儿科二线抗逆转录病毒治疗（第ART）结果的数据是稀缺的，但评估二线和设计第三行方案是必不可少的。

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来源
《Journal of tropical pediatrics. 》 |2017年第2期| 共9页
作者
Boerma Ragna S.; Kityo Cissy; Boender T. Sonia; Kaudha Elizabeth; Kayiwa Joshua; Musiime Victor; Mukuye Andrew; Kiconco Mary; Nankya Immaculate; Nakatudde Lilian; Mugyenyi Peter N.; van Hensbroek Michael Boele; de Wit Tobias F. Rinke; Sigaloff Kim C. E.; Calis Job C. J.;
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作者单位

Univ Amsterdam Acad Med Ctr Amsterdam Inst Global Hlth &

Dev Dept Global Hlth Amsterdam;

Joint Clin Res Ctr Kampala Uganda;

Univ Amsterdam Acad Med Ctr Amsterdam Inst Global Hlth &

Dev Dept Global Hlth Amsterdam;

Joint Clin Res Ctr Kampala Uganda;

Joint Clin Res Ctr Kampala Uganda;

Makerere Coll Hlth Sci Dept Pediat &

Child Hlth Kampala Uganda;

Joint Clin Res Ctr Kampala Uganda;

Joint Clin Res Ctr Kampala Uganda;

Joint Clin Res Ctr Kampala Uganda;

Joint Clin Res Ctr Kampala Uganda;

Joint Clin Res Ctr Kampala Uganda;

Univ Amsterdam Acad Med Ctr Global Child Hlth Grp Emma Childrens Hosp Amsterdam Netherlands;

Univ Amsterdam Acad Med Ctr Amsterdam Inst Global Hlth &

Dev Dept Global Hlth Amsterdam;

Univ Amsterdam Acad Med Ctr Amsterdam Inst Global Hlth &

Dev Dept Global Hlth Amsterdam;

Univ Amsterdam Acad Med Ctr Global Child Hlth Grp Emma Childrens Hosp Amsterdam Netherlands;

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原文格式 PDF
正文语种 eng
中图分类儿科学 ;
关键词
HIV-1; antiretroviral treatment; second-line; HIV drug resistance; genotypic resistance testing;

机译：HIV-1;抗逆转录病毒治疗;二线;艾滋病毒耐药;基因型抗性测试;

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专利

1. Second-line HIV Treatment in Ugandan Children: Favorable Outcomes and No Protease Inhibitor Resistance [J] . Boerma Ragna S., Kityo Cissy, Boender T. Sonia, Journal of tropical pediatrics. . 2017 ,第2期

机译：乌干达儿童的二线艾滋病毒治疗：有利的结果和蛋白酶抑制剂抗性
2. Treatment outcomes of over 1000 patients on second-line, protease inhibitor-based antiretroviral therapy from four public-sector HIV treatment facilities across Johannesburg, South Africa [J] . Shearer Kate, Evans Denise, Moyo Faith, Tropical Medicine and International Health: TM and IH . 2017 ,第2期

机译：在南非约翰内斯堡的四个公共部门艾滋病毒治疗设施的二线蛋白抑制剂的抗逆转录病毒治疗超过1000名患者的治疗结果
3. Adoption of evidence-informed guidelines in prescribing protease inhibitors for HIV-Tuberculosis co-infected patients on rifampicin and effects on HIV treatment outcomes in Uganda [J] . Mulindwa Frank, Castelnuovo Barbara, Kirenga Bruce, BMC Infectious Diseases . 2021 ,第1期

机译：采用证据知识的指导蛋白酶抑制剂对乌干达艾滋病毒治疗结果的艾滋病毒 - 结核病有关患者的规定蛋白酶抑制剂及对乌干达的影响
4. Probabilistic Neural Network for Predicting Resistance to HIV-Protease Inhibitor Nelfinavir [C] . Leticia Martins Raposo, Monica Barcellos Arruda, Rodrigo de Moraes Brindeiro, International Conference on Bioinformatics Models, Methods and Algorithms . 2014

机译：用于预测HIV蛋白酶抑制剂Nelfinavir抗性的概率神经网络
5. HIV, Cardiovascular Disease, Anti-retroviral Resistance: The Issue with Protease Inhibitors and a Need for Alternatives [D] . Gillcrist, Marion. 2020

机译：艾滋病毒，心血管疾病，抗逆转录病毒抗性：蛋白酶抑制剂的问题和需要替代品
6. Complex Patterns of Protease Inhibitor Resistance among Antiretroviral Treatment-Experienced HIV-2 Patients from Senegal: Implications for Second-Line Therapy [O] . Dana N. Raugi, Robert A. Smith, Selly Ba, 2013

机译：塞内加尔抗逆转录病毒治疗经验丰富的HIV-2患者中蛋白酶抑制剂耐药的复杂模式：对二线疗法的影响。
7. Second-line HIV Treatment in Ugandan Children: Favorable Outcomes and No Protease Inhibitor Resistance [O] . Ragna S. Boerma, Cissy Kityo, T. Sonia Boender, 2016

机译：乌干达儿童的二线艾滋病毒治疗：有利的结果和蛋白酶抑制剂抗性

Second-line HIV Treatment in Ugandan Children: Favorable Outcomes and No Protease Inhibitor Resistance

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