The TiME Trial: A Fully Embedded, Cluster-Randomized, Pragmatic Trial of Hemodialysis Session Duration

Dember Laura M.; Lacson Eduardo Jr.; Brunelli Steven M.; Hsu Jesse Y.; Cheung Alfred K.; Daugirdas John T.; Greene Tom; Kovesdy Csaba P.; Miskulin Dana C.; Thadhani Ravi I; Winkelmayer Wolfgang C.; Ellenberg Susan S.; Cifelli Denise; Madigan Rosemary; Young Amy; Angeletti Michael; Wingard Rebecca L.; Kahn Christina; Nissenson Allen R.; Maddux Franklin W.; Abbott Kevin C.; Landis J. Richard

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The TiME Trial: A Fully Embedded, Cluster-Randomized, Pragmatic Trial of Hemodialysis Session Duration

机译：时间试验：完全嵌入，簇随机化，血液透析会话持续时间的务实试验

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Background Data from clinical trials to inform practice in maintenance hemodialysis are limited. Incorporating randomized trials into dialysis clinical care delivery should help generate practice-guiding evidence, but the feasibility of this approach has not been established.

机译：来自临床试验以告知维护血液透析的实践的背景数据有限。将随机试验纳入透析临床护理递送，应该有助于产生实践指导证据，但尚未建立这种方法的可行性。

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来源
《Journal of the American Society of Nephrology: JASN》 |2019年第5期|共14页
作者
Dember Laura M.; Lacson Eduardo Jr.; Brunelli Steven M.; Hsu Jesse Y.; Cheung Alfred K.; Daugirdas John T.; Greene Tom; Kovesdy Csaba P.; Miskulin Dana C.; Thadhani Ravi I; Winkelmayer Wolfgang C.; Ellenberg Susan S.; Cifelli Denise; Madigan Rosemary; Young Amy; Angeletti Michael; Wingard Rebecca L.; Kahn Christina; Nissenson Allen R.; Maddux Franklin W.; Abbott Kevin C.; Landis J. Richard;
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作者单位

Univ Penn Perelman Sch Med Renal Electrolyte &

Hypertens Div Dept Med Philadelphia PA 19104 USA;

Fresenius Med Care North Amer Div Nephrol Waltham MA USA;

DaVita Clin Res Minneapolis MN USA;

Univ Penn Perelman Sch Med Dept Biostat Epidemiol &

Informat Philadelphia PA 19104 USA;

Univ Utah Dept Internal Med Div Nephrol &

Hypertens Salt Lake City UT 84112 USA;

Univ Illinois Dept Med Div Nephrol Coll Med Chicago Chicago IL USA;

Univ Utah Dept Populat Hlth Sci Salt Lake City UT USA;

Univ Tennessee Ctr Hlth Sci Div Nephrol Dept Med Memphis TN 38163 USA;

Tufts Med Ctr Div Nephrol Boston MA 02111 USA;

Massachusetts Gen Hosp Div Nephrol Boston MA 02114 USA;

Baylor Coll Med Dept Med Selzman Inst Kidney Hlth Sect Nephrol Houston TX 77030 USA;

Univ Penn Perelman Sch Med Dept Biostat Epidemiol &

Informat Philadelphia PA 19104 USA;

Univ Penn Perelman Sch Med Ctr Clin Epidemiol &

Biostat Philadelphia PA 19104 USA;

Univ Penn Perelman Sch Med Ctr Clin Epidemiol &

Biostat Philadelphia PA 19104 USA;

DaVita Clin Res Minneapolis MN USA;

Fresenius Med Care North Amer Div Nephrol Waltham MA USA;

Fresenius Med Care North Amer Div Nephrol Waltham MA USA;

Fresenius Med Care North Amer Div Nephrol Waltham MA USA;

DaVita Kidney Care El Segundo CA USA;

Fresenius Med Care North Amer Div Nephrol Waltham MA USA;

NIDDK NIH Bethesda MD 20892 USA;

Univ Penn Perelman Sch Med Dept Biostat Epidemiol &

Informat Philadelphia PA 19104 USA;

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原文格式 PDF
正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
关键词
TiME Trial; dialysis session duration; learning health system; NIH Health Care Systems Research Collaboratory; opt-out consent; consent waiver;

机译：时间试验;透析会话持续时间;学习卫生系统;NIH卫生保健系统研究协作;退出同意;同意豁免;

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专利

1. The TiME Trial: A Fully Embedded, Cluster-Randomized, Pragmatic Trial of Hemodialysis Session Duration [J] . Dember Laura M., Lacson Eduardo Jr., Brunelli Steven M., Journal of the American Society of Nephrology: JASN . 2019,第5期

机译：时间试验：完全嵌入，簇随机化，血液透析会话持续时间的务实试验
2. Enhancing SKIN health and safety in aged CARE (SKINCARE Trial): a study protocol for an exploratory cluster-randomized pragmatic trial [J] . Jan Kottner, Elisabeth Hahnel, Monira El Genedy, Trials . 2019,第1期

机译：增强老年CARE的皮肤健康和安全性（SKINCARE试验）：一项探索性整群随机实用研究的研究方案
3. The feasibility and acceptability of trial procedures for a pragmatic randomised controlled trial of a structured physical activity intervention for people diagnosed with colorectal cancer: findings from a pilot trial of cardiac rehabilitation versus usual care (no rehabilitation) with an embedded qualitative study [J] . Gill Hubbard, Ronan O’Carroll, Julie Munro, Pilot and Feasibility Studies . 2016,第1期

机译：一项针对被诊断为大肠癌的患者进行的结构性体育活动干预的实用随机对照试验的试验程序的可行性和可接受性：心脏康复与常规护理（无康复）的初步试验结果以及一项嵌入式定性研究
4. A novel method to generalize time-frequency coherence analysis between EEG or EMG signals during repetitive trials with high intra-subject variability in duration [C] . Maxime Fauvet, Sylvain Cremoux, Alexandre Chalard, International IEEE/EMBS Conference on Neural Engineering . 2019

机译：一种新的方法，可以在重复性试验中对脑电或肌电信号之间的时频相干分析进行概括，且持续时间较高
5. Longer Right Colon Withdrawal Time and Retroflexion Duration Significantly Increases Adenoma Detection Rate: A Randomized Controlled Trial at Three Endoscopy Centers [D] . Faisal, Mir Fahad. 2018

机译：较长的右冒号戒断时间和逆转反持续时间显着提高腺瘤检测率：三个内窥镜检查中心的随机对照试验
6. The feasibility and acceptability of trial procedures for a pragmatic randomised controlled trial of a structured physical activity intervention for people diagnosed with colorectal cancer: findings from a pilot trial of cardiac rehabilitation versus usual care (no rehabilitation) with an embedded qualitative study [O] . Gill Hubbard, Ronan O’Carroll, Julie Munro, 2016

机译：针对患有大肠癌的患者进行的结构性体育活动干预的实用随机对照试验的试验程序的可行性和可接受性：心脏康复与常规护理（无康复）的先导试验结果以及嵌入式定性研究
7. Improving Veteran Access to Integrated Management of Back Pain (AIM-Back): Protocol for an Embedded Pragmatic Cluster-Randomized Trial [O] . Steven Z George, Cynthia J Coffman, Kelli D Allen, 2020

机译：改善退伍军人访问背部疼痛的综合管理（瞄准）：嵌入式务实组随机试验的协议

The TiME Trial: A Fully Embedded, Cluster-Randomized, Pragmatic Trial of Hemodialysis Session Duration

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