Effects of the brain-derived neurotropic factor variant Val66Met on cortical structure in late childhood and early adolescence

de Araujo Celia Maria; Zugman Andre; Swardfager Walter; Nogueira Belangero Sintia Iole; Ota Vanessa Kiyomi; Spindola Leticia Maria; Hakonarson Hakon; Pellegrino Renata; Gadelha Ary; Salum Giovanni Abrahao; Pan Pedro Mario; de Moura Luciana Monteiro; Del Aquilla Marco; Picon Felipe Almeida; Amaro Edson Jr.; Sato Joao Ricardo; Brietzke Elisa; Grassi-Oliveira Rodrigo; Rohde Luis Augusto P.; Miguel Euripedes Constantino; Bressan Rodrigo A.; Jackowski Andrea Parolin

首页> 外文期刊>Journal of psychiatric research >Effects of the brain-derived neurotropic factor variant Val66Met on cortical structure in late childhood and early adolescence

【24h】

Effects of the brain-derived neurotropic factor variant Val66Met on cortical structure in late childhood and early adolescence

机译：脑衍生的神经致因子变异Val66met对儿童和早期青春期皮质结构的影响

获取原文

获取原文并翻译 | 示例

获取外文期刊封面目录资料

开具论文收录证明 >>

文献代查 >>

文献数据库（团队版） >>

页面导航

摘要
著录项
引文网络
相似文献
相关主题

摘要

Background: The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism (rs6265) has been associated with several neuropsychiatric disorders and regional structural brain changes in adults, but little is known about Val66Met's effect on brain morphology during typical or atypical neurodevelopment. Windows of vulnerability to psychopathology may be associated with the different alleles of the Val66Met polymorphism during childhood and adolescence.

机译：背景：脑衍生的神经营养因子（BDNF）Val66mmet多态性（RS6265）与成人的几种神经精神疾病和区域结构脑变化有关，但在典型或非典型神经发作期间对Val66met对脑形态的影响很少。易受伤害的窗户可能与童年和青春期的Val66met多态性的不同等位基因相关联。

著录项

来源
《Journal of psychiatric research》 |2018年第2018期|共8页
作者
de Araujo Celia Maria; Zugman Andre; Swardfager Walter; Nogueira Belangero Sintia Iole; Ota Vanessa Kiyomi; Spindola Leticia Maria; Hakonarson Hakon; Pellegrino Renata; Gadelha Ary; Salum Giovanni Abrahao; Pan Pedro Mario; de Moura Luciana Monteiro; Del Aquilla Marco; Picon Felipe Almeida; Amaro Edson Jr.; Sato Joao Ricardo; Brietzke Elisa; Grassi-Oliveira Rodrigo; Rohde Luis Augusto P.; Miguel Euripedes Constantino; Bressan Rodrigo A.; Jackowski Andrea Parolin;
展开▼
作者单位

Natl Inst Dev Psychiat Children &

Adolescents INC Sao Paulo Brazil;

Natl Inst Dev Psychiat Children &

Adolescents INC Sao Paulo Brazil;

Univ Toronto Dept Pharmacol &

Toxicol Toronto ON Canada;

Natl Inst Dev Psychiat Children &

Adolescents INC Sao Paulo Brazil;

Univ Fed Sao Paulo Dept Psychiat Sao Paulo Brazil;

Univ Fed Sao Paulo Dept Psychiat Sao Paulo Brazil;

Childrens Hosp Philadelphia Ctr Appl Genom Philadelphia PA 19104 USA;

Childrens Hosp Philadelphia Ctr Appl Genom Philadelphia PA 19104 USA;

Natl Inst Dev Psychiat Children &

Adolescents INC Sao Paulo Brazil;

Natl Inst Dev Psychiat Children &

Adolescents INC Sao Paulo Brazil;

Natl Inst Dev Psychiat Children &

Adolescents INC Sao Paulo Brazil;

Univ Fed ABC Math &

Stat Inst Santo Andre Brazil;

Natl Inst Dev Psychiat Children &

Adolescents INC Sao Paulo Brazil;

Natl Inst Dev Psychiat Children &

Adolescents INC Sao Paulo Brazil;

Univ Sao Paulo Inst Radiol INRAD Sao Paulo Brazil;

Natl Inst Dev Psychiat Children &

Adolescents INC Sao Paulo Brazil;

Univ Fed Sao Paulo Dept Psychiat Sao Paulo Brazil;

Pontificia Univ Catolica Rio Grande do Sul DCNL Porto Alegre RS Brazil;

Natl Inst Dev Psychiat Children &

Adolescents INC Sao Paulo Brazil;

Natl Inst Dev Psychiat Children &

Adolescents INC Sao Paulo Brazil;

Natl Inst Dev Psychiat Children &

Adolescents INC Sao Paulo Brazil;

Natl Inst Dev Psychiat Children &

Adolescents INC Sao Paulo Brazil;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学;
关键词
Brain-derived neurotrophic factor; BDNF; rs6265; Val66Met; Children; Adolescents; Psychiatric disorders; Brain morphology; MRI; Cortical thickness;

机译：脑衍生的神经营养因子;BDNF;RS6265;VAL66MET;儿童;青少年;精神病疾病;脑形态;MRI;皮质厚度;皮质厚度;

相似文献

外文文献
中文文献
专利

1. Effects of the brain-derived neurotropic factor variant Val66Met on cortical structure in late childhood and early adolescence [J] . de Araujo Celia Maria, Zugman Andre, Swardfager Walter, Journal of psychiatric research . 2018,第期

机译：脑衍生的神经致因子变异Val66met对儿童和早期青春期皮质结构的影响
2. The Brain-Derived Neurotrophic Factor Val66Met Polymorphism Moderates the Effects of Childhood Abuse on Severity of Depressive Symptoms in a Time-Dependent Manner [J] . Caitlin Webb, Jane M. Gunn, Maria Potiriadis, Frontiers in Psychiatry . 2016,第1期

机译：脑源性神经营养因子Val66Met多态性以时间依赖性方式减轻了儿童期虐待对抑郁症状严重程度的影响。
3. Gender-Specific Effects of Brain-Derived Neurotrophic Factor Val66Met Polymorphism and Childhood Maltreatment on Anxiety [J] . Min Jung-Ah, Lee Heon-Jeong, Lee Seung-Hwan, Neuropsychobiology . 2013,第1期

机译：脑源性神经营养因子Val66Met多态性和儿童期虐待对焦虑的性别特异性影响
4. Impact of genetic variant BDNF (Val66Met) on brain structure and function [C] . Zhe-Yu Chen, Kevin Bath, Bruce McEwen, Symposium on Growth Factors and Psychiatric Disorders . 2008

机译：遗传变体BDNF（Val66met）对脑结构与功能的影响
5. Toward Precision Medicine: Effects of the Common VAL66met BDNF Variant in the Aging Brain and Implications for the Future of Parkinson’S Disease Therapeutics [D] . Mercado-Idziak, Natosha Marie. 2021

机译：朝着精密药物：普通Val66mmet BDNF变异在老化脑老龄化的影响和对帕金森病治疗的未来的影响
6. Influence of childhood trauma and brain-derived neurotrophic factor Val66Met polymorphism on posttraumatic stress symptoms and cortical thickness [O] . Min Jin Jin, Hyeonjin Jeon, Myoung Ho Hyun, -1

机译：儿童创伤和脑源性神经营养因子Val66Met多态性对创伤后应激症状和皮层厚度的影响
7. Influence of childhood trauma and brain-derived neurotrophic factor Val66Met polymorphism on posttraumatic stress symptoms and cortical thickness [O] . Min Jin Jin, Hyeonjin Jeon, Myoung Ho Hyun, 2019

机译：儿童创伤和脑源性神经营养因子Val66mmet多态性对心痛症状和皮质厚度的影响

Effects of the brain-derived neurotropic factor variant Val66Met on cortical structure in late childhood and early adolescence

摘要

著录项

引文网络

相似文献

相关主题

期刊订阅