Pre-Emptive Value of Methylprednisolone Intravenous Infusion in Patients With Vertebral Metastases. A Double-Blind Randomized Study

摘要

Context. The vertebral column is the most common site of bone metastases irrespective of the primary tumor. Vertebral metastases are a major cause of motor deficit of the lower extremities. The use of radiotherapy is the treatment of choice in these patients. A temporary worsening of pain shortly during the course of palliative radiotherapy is clinically a common problem. Steroid infusion has well-documented neuroprotective effects.