Reproducible quantification of IgG uptake at endogenous and overexpressed FcRn levels at pH 7.4: Comparison of a wild type IgG and a stronger FcRn binding variant

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Reproducible quantification of IgG uptake at endogenous and overexpressed FcRn levels at pH 7.4: Comparison of a wild type IgG and a stronger FcRn binding variant

机译：pH 7.4在pH 7.4的内源性和过表达FCRN水平下的IgG摄取的可再现定量：野生型IgG的比较和更强的FCRN结合变体

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《Journal of Immunological Methods》 |2020年第2020期|共6页
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正文语种 eng
中图分类医学免疫学;
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1. Reproducible quantification of IgG uptake at endogenous and overexpressed FcRn levels at pH 7.4: Comparison of a wild type IgG and a stronger FcRn binding variant [J] . Journal of Immunological Methods . 2020,第期

机译：pH 7.4在pH 7.4的内源性和过表达FCRN水平下的IgG摄取的可再现定量：野生型IgG的比较和更强的FCRN结合变体
2. Evaluation of an FcRn affinity chromatographic method for IgG1-type antibodies and evaluation of IgG variants [J] . Cymer Florian, Schlothauer Tilman, Knaupp Alexander, Bioanalysis . 2017,第17期

机译：用于IgG1型抗体的FCRN亲和色谱法评价及IgG变体评价
3. Identification of IgG(1) variants with increased affinity to FcgammaRIIIa and unaltered affinity to FcgammaRI and FcRn: comparison of soluble receptor-based and cell-based binding assays. [J] . Lu Y, Vernes JM, Chiang N, Journal of Immunological Methods . 2011,第1a2期

机译：与FcgammaRIIIa的亲和力增加而对FcgammaRI和FcRn的亲和力不变的IgG（1）变体的鉴定：基于可溶性受体和细胞的结合测定的比较。
4. IgG Variants with Increased FcRn Binding: Impact on Effector Functions [C] . Celine Monnet, Sylvie Jorieux, Nathalie Fournier, PEGS . 2015

机译：IgG变体具有增加的FCRN结合：对效应器功能的影响
5. Identification of human IgG1 variant with enhanced FcRn binding and without increased binding to rheumatoid factor autoantibody [O] . Atsuhiko Maeda, Yuki Iwayanagi, Kenta Haraya, 2017

机译：鉴定具有增强的FcRn结合且不增加与类风湿因子自身抗体结合的人IgG1变体
6. High Resolution Mapping of the Binding Site on Human IgG1 for FcγRI, FcγRII, FcγRIII, and FcRn and Design of IgG1 Variants with Improved Binding to the FcγR [O] . Robert L. Shields, Angela K. Namenuk, Kyu Hong, 2001

机译：用于FCγRI，FCγRII，FCγRIII和FCRN的粘合位点的高分辨率映射，以及改善与FCγR的结合的IgG1变体的设计

Reproducible quantification of IgG uptake at endogenous and overexpressed FcRn levels at pH 7.4: Comparison of a wild type IgG and a stronger FcRn binding variant

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