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Cost‐effectiveness of the Family Nurse Partnership (FNP) programme in England: Evidence from the building blocks trial

机译:英格兰家族护士伙伴关系(FNP)计划的成本效益:来自建筑物的证据

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Abstract Rational, aims, and objectives The Family Nurse Partnership (FNP) is a licensed intensive home visiting intervention developed in the United States. It has been provided in England by the Department of Health since 2006. The Building Blocks trial assessed the effectiveness and cost‐effectiveness of FNP in England. Methods We performed a cost‐utility analysis (National Health Service (NHS) perspective) alongside the Building Blocks trial (over 2.5?y). The analysis was conducted in accordance with National Institute for Health and Clinical Excellence (NICE) reference case standards. Health‐related quality of life was elicited from mothers using the EQ‐5D‐3L. Resource‐use data were collected from self‐reported questionnaires, Hospital Episode Statistics, general practitioner records and the central Department of Health FNP database. Costs and quality‐adjusted life years (QALYs) were discounted at 3.5%. The base case analysis used an intention to treat approach on the imputed dataset using multiple imputation. Results The FNP intervention costs on average £1812 more per participant compared to usual care (95% confidence interval: ?£2700; £5744). Incremental adjusted mean QALYs are marginally higher for FNP (mean difference 0.0036, 95% confidence interval: ?0.017; 0.025). The probability of FNP being cost‐effective is less than 20% given the current NICE willingness to pay threshold of £20?000 per additional QALY. The results were robust to sensitivity analyses. Conclusion Given the absence of significant benefits of FNP in terms of the primary outcomes of the trial and only marginal maternal QALY gains, FNP does not represent a cost‐effective intervention when compared with existing services already offered to young pregnant women.
机译:摘要理性,目标和目标家庭护士伙伴关系(FNP)是美国在美国开发的许可集中的家庭参观干预措施。自2006年以来,在卫生部提供了在英格兰提供。该建筑物审判评估了英国FNP的有效性和成本效益。方法我们对建筑物块试验(超过2.5 y)进行成本实用分析(国家卫生服务(NHS)视角)。该分析根据国家健康和临床卓越(漂亮)参考案例标准进行。使用EQ-5D-3L,从母亲中引发了与健康相关的生活质量。资源使用数据从自我报告的问卷调查,医院发作统计数据,一般从业者记录和卫生部的中央部FNP数据库中收集。成本和质量调整的终身年(QALYS)折扣为3.5%。基本情况分析使用多种归纳使用意图在潜在的数据集上处理方法。结果与通常的护理相比,每位参与者平均每年1812英镑的FNP干预费用(95%的置信区间:?2700英镑;£5744)。增量调整平均值qalys对于fnp来说略高(平均差异0.0036,95%置信区间:0.017; 0.025)。鉴于目前愿意支付每额外QALY的20英镑£20,000英镑的普通率,FNP成本效益的概率小于20%。结果对敏感性分析具有鲁棒性。结论鉴于在审判的主要结果和唯一的边际孕产QALY收益方面没有FNP的显着效益,与已经向年轻人孕妇提供的现有服务相比,FNP并不代表成本效益的干预。

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