The diminishing value of the Physicians' Desk Reference and drug package inserts as a medical and legal standard of medical usage of pharmaceutical drugs.

摘要

In the legal arena, the Physician's Desk Reference (PDR) is often held to be the standard for medical usage of pharmaceutical drugs.1 It is used by attorneys as a resource to support testimony that a certain adverse effect can occur with a drug and that the manufacturer or physician knew or should have known about it. It is used as an impeachment tool if a pharmaceutical manufacturer or physician denies knowledge of a particular adverse effect or disputes the existence of the adverse effects.