Synthesis, characterization and single crystal X-ray structures of oxidovanadium(V) complexes derived from N'-(2-hydroxy-3-methoxybenzylidene)-3,5-dimethoxybenzohydrazide with antibacterial activity

摘要

A new oxidovanadium(V) complex, [VOL(OCH3)(CH3OH)] (1), was prepared from N'-(2-hydroxy-3-methoxybenzylidene)-3,5-dimethoxybenzohydrazide (H2L). Reaction of 1 with ethyl maltol (HL') in methanol afforded the new oxidovanadium(V) complex, [VOLL'] (2). The complexes were characterized by IR, UV and H-1 NMR spectra. Structures of the complexes were further confirmed by single crystal X-ray determination. The V ions in the complexes are octahedral. The hydrazone ligands coordinate to V through the phenolate O, imino N, and enolate O. The ethyl maltolate ligand coordinates to V through the carbonyl and hydroxy oxygens. Both complexes show effective antibacterial activity against B. subtilis, S. aureus and P. aeruginosa. Thermogravimetric analysis was also performed.