Treatment of a mobile intracardiac thrombus using ultra‐slow low‐dose tissue plasminogen activator in combination with heparin

摘要

Summary What is known and objective Free‐floating thrombi in the right heart occur in a subset of patients with pulmonary embolism with high rates of mortality if untreated. Treatment of choice is controversial and likely patient specific as studies have failed to consistently show a significant difference in mortality between options. Case summary We present a case of a 45‐year‐old female with a mobile right heart thrombus treated with ultra‐slow, low‐dose t‐ PA infusion in combination with heparin. What is new and conclusion Ultra‐slow, low‐dose infusion of t‐ PA may be an option for treatment of mobile intracardiac thrombi.